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I have searched DoodleKisses for an answer to this question but to no avail. Can Parastar Plus and Sentinel (or their equivalents) be given at the same time or should they be spaced days apart?

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I strongly believe in giving everything separately. It may be perfectly fine to give them at the same time, but if your dog happens to be one of those who is going to have a reaction to something, you won't know which it is if you give them together. And why hit their systems with more than one drug at a time if you can avoid it? 

I agree Karen. Separately is better for their system.

I always give them together.  Giving them separately would mean one more thing to do on my calendar!

1st and 15th is fairly easy. Or 15th and 30th. Some people pay their bills twice a month and that works too, lol. 

Just learned my lesson on this one!--I will always give them separately from now on--too hard on them too get hit with different drugs at once.

You may want to ask your Vet.  Mine is clear that they should only be given one at a time. 

I will check with my vet today, as Wynnie's right ear is red and has a little brown gunk. I am inclined to follow your advice and space out these medicines but I will ask the vet today and report back.
During my visit with the vet who was checking Wynnie's ear infection, I asked about whether or not Sentinel and Parastar Plus could be given at the same time. She indicated that when they are first administered, the vets in her practice recommend spacing them out to see if one of the medications has an adverse reaction to the pet. Once it is determined that no adverse reaction has occurred then she believes that the meds can be administered simultaneously. In fact, she give her dogs both products at the same time.

I also asked about the loading of the two drugs on the pet. She said that the Parastar Plus works on the oil glands in the skin and is transmitted along the skin. Very little is absorbed in the body itself. Sentinel, on the other hand, is internal.

In the final analysis, DoodleKisses seems to empahsize that owners should do what they are comfortable with. I feel comfortable spacing them as Karen has suggested but if pressed by time or travel constraints, I will give both doses simultaneously. However, I do plan to phase in the spacing ever so gradually so as not to endanger my precious girl's health.

Even though a dog may not have a reaction to either mediation - there can be a reaction when both are given together, even if they work in different ways.  They are both types of poison and put stress on the animal.  Both medications can lower a dog's seizure threshold.

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